Lamin A and the LINC complex act as potential tumor suppressors in Ewing Sarcoma
Lamin A and the LINC complex act as potential tumor suppressors in Ewing Sarcoma
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Lamin A, a main constituent of the nuclear lamina, is involved in mechanosignaling and cell migration through dynamic interactions with the LINC complex, formed by the nuclear envelope proteins SUN1, SUN2 and the nesprins. Here, we investigated lamin A role in Ewing Sarcoma (EWS), an aggressive bone tumor affecting children and young adults. In pat...
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Lamin A and the LINC complex act as potential tumor suppressors in Ewing Sarcoma
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TN_cdi_doaj_primary_oai_doaj_org_article_5d5b516d43e64786927cb4086677f8b3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5d5b516d43e64786927cb4086677f8b3
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-022-04729-5
