Effects of RARα ligand binding domain mutations on breast fibroepithelial tumor function and signali...
Effects of RARα ligand binding domain mutations on breast fibroepithelial tumor function and signaling
About this item
Full title
Author / Creator
Huang, Xi Xiao , Ng, Ley Moy , Lee, Po-Hsien , Guan, Peiyong , Chow, Mun Juinn , Bashir, Aisyah Binte Mohamed , Lau, Meina , Tan, Kenric Yi Shu , Li, Zhimei , Chan, Jason Yongsheng , Hong, Jing Han , Ng, Sheng Rong , Ko, Tun Kiat , Heng, Hong Lee , Teo, Hsiang Ling , Rhodes, Daniela , Tan, Patrick , Tan, Puay Hoon , McDonnell, Donald P. and Teh, Bin Tean
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Point mutations in the ligand binding domain of retinoic acid receptor alpha (RARα) are linked to breast fibroepithelial tumor development, but their role in solid tumorigenesis is unclear. In this study, we assessed the functional effects of known RARα mutations on retinoic acid signaling using biochemical and cellular assays. All tested mutants e...
Alternative Titles
Full title
Effects of RARα ligand binding domain mutations on breast fibroepithelial tumor function and signaling
Authors, Artists and Contributors
Author / Creator
Ng, Ley Moy
Lee, Po-Hsien
Guan, Peiyong
Chow, Mun Juinn
Bashir, Aisyah Binte Mohamed
Lau, Meina
Tan, Kenric Yi Shu
Li, Zhimei
Chan, Jason Yongsheng
Hong, Jing Han
Ng, Sheng Rong
Ko, Tun Kiat
Heng, Hong Lee
Teo, Hsiang Ling
Rhodes, Daniela
Tan, Patrick
Tan, Puay Hoon
McDonnell, Donald P.
Teh, Bin Tean
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5d8d627c841a4ee3b88f4b824ec50acd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5d8d627c841a4ee3b88f4b824ec50acd
Other Identifiers
ISSN
2374-4677
E-ISSN
2374-4677
DOI
10.1038/s41523-024-00716-5
