Eosinophils preserve bone homeostasis by inhibiting excessive osteoclast formation and activity via...
Eosinophils preserve bone homeostasis by inhibiting excessive osteoclast formation and activity via eosinophil peroxidase
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Eosinophils are involved in tissue homeostasis. Herein, we unveiled eosinophils as important regulators of bone homeostasis. Eosinophils are localized in proximity to bone-resorbing osteoclasts in the bone marrow. The absence of eosinophils in ΔdblGATA mice results in lower bone mass under steady-state conditions and amplified bone loss upon sex ho...
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Full title
Eosinophils preserve bone homeostasis by inhibiting excessive osteoclast formation and activity via eosinophil peroxidase
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TN_cdi_doaj_primary_oai_doaj_org_article_5da2f219e2984371a8d14992bdd17d44
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5da2f219e2984371a8d14992bdd17d44
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-45261-8
