NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions
NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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NLRC5 is a transcriptional regulator of MHC class I (MHCI), which maintains high MHCI expression particularly in T cells. Recent evidence highlights an important NK–T-cell crosstalk, raising the question on whether NLRC5 specifically modulates this interaction. Here we show that NK cells from
Nlrc5
-deficient mice exhibit moderate alterations...
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NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions
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TN_cdi_doaj_primary_oai_doaj_org_article_5daa48a82f9b456488d8d66573ddc116
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5daa48a82f9b456488d8d66573ddc116
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms10554
