Multiplex RNA‐based detection of clinically relevant MET alterations in advanced non‐small cell lung...
Multiplex RNA‐based detection of clinically relevant MET alterations in advanced non‐small cell lung cancer
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Author / Creator
Aguado, Cristina , Teixido, Cristina , Román, Ruth , Reyes, Roxana , Giménez‐Capitán, Ana , Marin, Elba , Cabrera, Carlos , Viñolas, Nuria , Castillo, Sergi , Muñoz, Silvia , Arcocha, Ainara , López‐Vilaró, Laura , Sullivan, Ivana , Aldeguer, Erika , Rodríguez, Sonia , Moya, Irene , Viteri, Santiago , Cardona, Andrés Felipe , Palmero, Ramon , Sainz, Cristina , Mesa‐Guzmán, Miguel , Lozano, Maria D. , Aguilar‐Hernández, Andrés , Martínez‐Bueno, Alejandro , González‐Cao, María , Gonzalvo, Elena , Leenders, William P. J. , Rosell, Rafael , Montuenga, Luis M. , Prat, Aleix , Molina‐Vila, Miguel A. and Reguart, Noemi
Publisher
United States: John Wiley & Sons, Inc
Journal title
Language
English
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Publication information
Publisher
United States: John Wiley & Sons, Inc
Subjects
More information
Scope and Contents
Contents
We studied MET alterations in 474 advanced non‐small‐cell lung cancer (NSCLC) patients by nCounter, an RNA‐based technique. We identified 3% with METΔex14 mRNA and 3.5% with very‐high MET mRNA expression, a surrogate of MET amplification. MET alterations identified by nCounter correlated with clinical benefit from MET inhibitors. Quantitative mRNA‐...
Alternative Titles
Full title
Multiplex RNA‐based detection of clinically relevant MET alterations in advanced non‐small cell lung cancer
Authors, Artists and Contributors
Author / Creator
Teixido, Cristina
Román, Ruth
Reyes, Roxana
Giménez‐Capitán, Ana
Marin, Elba
Cabrera, Carlos
Viñolas, Nuria
Castillo, Sergi
Muñoz, Silvia
Arcocha, Ainara
López‐Vilaró, Laura
Sullivan, Ivana
Aldeguer, Erika
Rodríguez, Sonia
Moya, Irene
Viteri, Santiago
Cardona, Andrés Felipe
Palmero, Ramon
Sainz, Cristina
Mesa‐Guzmán, Miguel
Lozano, Maria D.
Aguilar‐Hernández, Andrés
Martínez‐Bueno, Alejandro
González‐Cao, María
Gonzalvo, Elena
Leenders, William P. J.
Rosell, Rafael
Montuenga, Luis M.
Prat, Aleix
Molina‐Vila, Miguel A.
Reguart, Noemi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5db041644f0248ee90bd178c373b1867
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5db041644f0248ee90bd178c373b1867
Other Identifiers
ISSN
1574-7891
E-ISSN
1878-0261
DOI
10.1002/1878-0261.12861
