Amphetamine pretreatment blunts dopamine-induced D2/D3-receptor occupancy by an arrestin-mediated me...
Amphetamine pretreatment blunts dopamine-induced D2/D3-receptor occupancy by an arrestin-mediated mechanism: A PET study in internalization compromised mice
About this item
Full title
Author / Creator
Publisher
United States: Elsevier Inc
Journal title
Language
English
Formats
Publication information
Publisher
United States: Elsevier Inc
Subjects
More information
Scope and Contents
Contents
•PET was employed in β-arrestin-2 knock-out mice to study receptor internalization.•[11C]Raclopride was used to study D2/D3 receptor occupancy and binding potential.•Knock-out mice exhibited preserved occupancy to repeated amphetamine challenge.•Wild-type mice showed severely blunted occupancy on repeated amphetamine challenge.•PET binding was depr...
Alternative Titles
Full title
Amphetamine pretreatment blunts dopamine-induced D2/D3-receptor occupancy by an arrestin-mediated mechanism: A PET study in internalization compromised mice
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5ed94a745c204b48af0a9eac7fa79ad9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5ed94a745c204b48af0a9eac7fa79ad9
Other Identifiers
ISSN
1053-8119,1095-9572
E-ISSN
1095-9572
DOI
10.1016/j.neuroimage.2023.120416
