Metallo-β-Lactamase Inhibitors Inspired on Snapshots from the Catalytic Mechanism
Metallo-β-Lactamase Inhibitors Inspired on Snapshots from the Catalytic Mechanism
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Publisher
Switzerland: MDPI
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Language
English
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Publisher
Switzerland: MDPI
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β-Lactam antibiotics are the most widely prescribed antibacterial drugs due to their low toxicity and broad spectrum. Their action is counteracted by different resistance mechanisms developed by bacteria. Among them, the most common strategy is the expression of β-lactamases, enzymes that hydrolyze the amide bond present in all β-lactam compounds....
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Full title
Metallo-β-Lactamase Inhibitors Inspired on Snapshots from the Catalytic Mechanism
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TN_cdi_doaj_primary_oai_doaj_org_article_5f1c5adc3b59468b945faa0b71aaa0e2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5f1c5adc3b59468b945faa0b71aaa0e2
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ISSN
2218-273X
E-ISSN
2218-273X
DOI
10.3390/biom10060854
