In vivo quantification of neurofibrillary tangles with [ 18 F]MK-6240
In vivo quantification of neurofibrillary tangles with [ 18 F]MK-6240
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Author / Creator
Pascoal, Tharick A , Shin, Monica , Kang, Min Su , Chamoun, Mira , Chartrand, Daniel , Mathotaarachchi, Sulantha , Bennacef, Idriss , Therriault, Joseph , Ng, Kok Pin , Hopewell, Robert , Bouhachi, Reda , Hsiao, Hung-Hsin , Benedet, Andrea L , Soucy, Jean-Paul , Massarweh, Gassan , Gauthier, Serge and Rosa-Neto, Pedro
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Imaging agents capable of quantifying the brain's tau aggregates will allow a more precise staging of Alzheimer's disease (AD). The aim of the present study was to examine the in vitro properties as well as the in vivo kinetics, using gold standard methods, of the novel positron emission tomography (PET) tau imaging agent [
F]MK-6240.
In vitr...
Alternative Titles
Full title
In vivo quantification of neurofibrillary tangles with [ 18 F]MK-6240
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TN_cdi_doaj_primary_oai_doaj_org_article_5f4fe21184f14dc5af0f1fcd48083ff4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5f4fe21184f14dc5af0f1fcd48083ff4
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ISSN
1758-9193
E-ISSN
1758-9193
DOI
10.1186/s13195-018-0402-y
