Surface-modified engineered exosomes attenuated cerebral ischemia/reperfusion injury by targeting th...
Surface-modified engineered exosomes attenuated cerebral ischemia/reperfusion injury by targeting the delivery of quercetin towards impaired neurons
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Author / Creator
Guo, Lin , Huang, Zhixuan , Huang, Lijuan , Liang, Jia , Wang, Peng , Zhao, Liang and Shi, Yijie
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
The incidence of ischemic stroke in the context of vascular disease is high, and the expression of growth-associated protein-43 (GAP43) increases when neurons are damaged or stimulated, especially in a rat model of middle cerebral artery occlusion/reperfusion (MCAO/R).
DESIGN: We bioengineered neuron-targeting exosomes (Exo) conjugated to a mono...
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Full title
Surface-modified engineered exosomes attenuated cerebral ischemia/reperfusion injury by targeting the delivery of quercetin towards impaired neurons
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TN_cdi_doaj_primary_oai_doaj_org_article_5fa50a0043fe4374a289804eeb9b41f1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5fa50a0043fe4374a289804eeb9b41f1
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ISSN
1477-3155
E-ISSN
1477-3155
DOI
10.1186/s12951-021-00879-4