Am80‐GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that r...
Am80‐GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia‐associated infection and mortality
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Neutrophils generated by granulocyte colony‐stimulating factor (GCSF) are functionally immature and, consequently, cannot effectively reduce infection and infection‐related mortality in cancer chemotherapy‐induced neutropenia (CCIN). Am80, a retinoic acid (RA) agonist that enhances granulocytic differentiation by selectively activating transcriptio...
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Full title
Am80‐GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia‐associated infection and mortality
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TN_cdi_doaj_primary_oai_doaj_org_article_5fb1b492eea045fd91994109b49a5171
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5fb1b492eea045fd91994109b49a5171
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ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.201606434
