Functional variants identify sex-specific genes and pathways in Alzheimer’s Disease
Functional variants identify sex-specific genes and pathways in Alzheimer’s Disease
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The incidence of Alzheimer’s Disease in females is almost double that of males. To search for sex-specific gene associations, we build a machine learning approach focused on functionally impactful coding variants. This method can detect differences between sequenced cases and controls in small cohorts. In the Alzheimer’s Disease Sequencing Project...
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Functional variants identify sex-specific genes and pathways in Alzheimer’s Disease
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TN_cdi_doaj_primary_oai_doaj_org_article_5fd507b11a1941148399c2ae7ff75fb9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5fd507b11a1941148399c2ae7ff75fb9
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-38374-z