Log in to save to my catalogue

Functional variants identify sex-specific genes and pathways in Alzheimer’s Disease

Functional variants identify sex-specific genes and pathways in Alzheimer’s Disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5fd507b11a1941148399c2ae7ff75fb9

Functional variants identify sex-specific genes and pathways in Alzheimer’s Disease

About this item

Full title

Functional variants identify sex-specific genes and pathways in Alzheimer’s Disease

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2023-05, Vol.14 (1), p.2765-2765, Article 2765

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The incidence of Alzheimer’s Disease in females is almost double that of males. To search for sex-specific gene associations, we build a machine learning approach focused on functionally impactful coding variants. This method can detect differences between sequenced cases and controls in small cohorts. In the Alzheimer’s Disease Sequencing Project...

Alternative Titles

Full title

Functional variants identify sex-specific genes and pathways in Alzheimer’s Disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5fd507b11a1941148399c2ae7ff75fb9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5fd507b11a1941148399c2ae7ff75fb9

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-023-38374-z

How to access this item