Widespread chromatin context-dependencies of DNA double-strand break repair proteins
Widespread chromatin context-dependencies of DNA double-strand break repair proteins
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
DNA double-strand breaks are repaired by multiple pathways, including non-homologous end-joining (NHEJ) and microhomology-mediated end-joining (MMEJ). The balance of these pathways is dependent on the local chromatin context, but the underlying mechanisms are poorly understood. By combining knockout screening with a dual MMEJ:NHEJ reporter inserted...
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Full title
Widespread chromatin context-dependencies of DNA double-strand break repair proteins
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TN_cdi_doaj_primary_oai_doaj_org_article_6009cbab086a43759a3f31b9c33c7f5d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6009cbab086a43759a3f31b9c33c7f5d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-49232-x
