Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis an...
Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease
About this item
Full title
Author / Creator
Youlten, Scott E. , Kemp, John P. , Logan, John G. , Ghirardello, Elena J. , Sergio, Claudio M. , Dack, Michael R. G. , Guilfoyle, Siobhan E. , Leitch, Victoria D. , Butterfield, Natalie C. , Komla-Ebri, Davide , Chai, Ryan C. , Corr, Alexander P. , Smith, James T. , Mohanty, Sindhu T. , Morris, John A. , McDonald, Michelle M. , Quinn, Julian M. W. , McGlade, Amelia R. , Bartonicek, Nenad , Jansson, Matt , Hatzikotoulas, Konstantinos , Irving, Melita D. , Beleza-Meireles, Ana , Rivadeneira, Fernando , Duncan, Emma , Richards, J. Brent , Adams, David J. , Lelliott, Christopher J. , Brink, Robert , Phan, Tri Giang , Eisman, John A. , Evans, David M. , Zeggini, Eleftheria , Baldock, Paul A. , Bassett, J. H. Duncan , Williams, Graham R. and Croucher, Peter I.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Osteocytes are master regulators of the skeleton. We mapped the transcriptome of osteocytes from different skeletal sites, across age and sexes in mice to reveal genes and molecular programs that control this complex cellular-network. We define an osteocyte transcriptome signature of 1239 genes that distinguishes osteocytes from other cells. 77% ha...
Alternative Titles
Full title
Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease
Authors, Artists and Contributors
Author / Creator
Kemp, John P.
Logan, John G.
Ghirardello, Elena J.
Sergio, Claudio M.
Dack, Michael R. G.
Guilfoyle, Siobhan E.
Leitch, Victoria D.
Butterfield, Natalie C.
Komla-Ebri, Davide
Chai, Ryan C.
Corr, Alexander P.
Smith, James T.
Mohanty, Sindhu T.
Morris, John A.
McDonald, Michelle M.
Quinn, Julian M. W.
McGlade, Amelia R.
Bartonicek, Nenad
Jansson, Matt
Hatzikotoulas, Konstantinos
Irving, Melita D.
Beleza-Meireles, Ana
Rivadeneira, Fernando
Duncan, Emma
Richards, J. Brent
Adams, David J.
Lelliott, Christopher J.
Brink, Robert
Phan, Tri Giang
Eisman, John A.
Evans, David M.
Zeggini, Eleftheria
Baldock, Paul A.
Bassett, J. H. Duncan
Williams, Graham R.
Croucher, Peter I.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_60182d9a653b4b4d9d0b7b34378bcb3e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_60182d9a653b4b4d9d0b7b34378bcb3e
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-22517-1
