Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight
Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight
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Author / Creator
Park, Jiwoon , Overbey, Eliah G. , Narayanan, S. Anand , Kim, JangKeun , Tierney, Braden T. , Damle, Namita , Najjar, Deena , Ryon, Krista A. , Proszynski, Jacqueline , Kleinman, Ashley , Hirschberg, Jeremy Wain , MacKay, Matthew , Afshin, Evan E. , Granstein, Richard , Gurvitch, Justin , Hudson, Briana M. , Rininger, Aric , Mullane, Sean , Church, Sarah E. , Meydan, Cem , Church, George , Beheshti, Afshin , Mateus, Jaime and Mason, Christopher E.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Spaceflight can change metabolic, immunological, and biological homeostasis and cause skin rashes and irritation, yet the molecular basis remains unclear. To investigate the impact of short-duration spaceflight on the skin, we conducted skin biopsies on the Inspiration4 crew members before (L-44) and after (R + 1) flight. Leveraging multi-omics ass...
Alternative Titles
Full title
Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight
Authors, Artists and Contributors
Author / Creator
Overbey, Eliah G.
Narayanan, S. Anand
Kim, JangKeun
Tierney, Braden T.
Damle, Namita
Najjar, Deena
Ryon, Krista A.
Proszynski, Jacqueline
Kleinman, Ashley
Hirschberg, Jeremy Wain
MacKay, Matthew
Afshin, Evan E.
Granstein, Richard
Gurvitch, Justin
Hudson, Briana M.
Rininger, Aric
Mullane, Sean
Church, Sarah E.
Meydan, Cem
Church, George
Beheshti, Afshin
Mateus, Jaime
Mason, Christopher E.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_60b54f6af6b24c2694a1e6a88a4f7b8d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_60b54f6af6b24c2694a1e6a88a4f7b8d
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-48625-2