PU.1 regulates Alzheimer's disease-associated genes in primary human microglia
PU.1 regulates Alzheimer's disease-associated genes in primary human microglia
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Author / Creator
Rustenhoven, Justin , Smith, Amy M , Smyth, Leon C , Jansson, Deidre , Scotter, Emma L , Swanson, Molly E V , Aalderink, Miranda , Coppieters, Natacha , Narayan, Pritika , Handley, Renee , Overall, Chris , Park, Thomas I H , Schweder, Patrick , Heppner, Peter , Curtis, Maurice A , Faull, Richard L M and Dragunow, Mike
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Microglia play critical roles in the brain during homeostasis and pathological conditions. Understanding the molecular events underpinning microglial functions and activation states will further enable us to target these cells for the treatment of neurological disorders. The transcription factor PU.1 is critical in the development of myeloid cells...
Alternative Titles
Full title
PU.1 regulates Alzheimer's disease-associated genes in primary human microglia
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_61d01fe126004e1d9256ea1766c25fa5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_61d01fe126004e1d9256ea1766c25fa5
Other Identifiers
ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/s13024-018-0277-1
