PTEN Protein Phosphatase Activity Is Not Required for Tumour Suppression in the Mouse Prostate
PTEN Protein Phosphatase Activity Is Not Required for Tumour Suppression in the Mouse Prostate
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Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Loss PTEN function is one of the most common events driving aggressive prostate cancers and biochemically, PTEN is a lipid phosphatase which opposes the activation of the oncogenic PI3K-AKT signalling network. However, PTEN also has additional potential mechanisms of action, including protein phosphatase activity. Using a mutant enzyme, PTEN Y138L,...
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Full title
PTEN Protein Phosphatase Activity Is Not Required for Tumour Suppression in the Mouse Prostate
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TN_cdi_doaj_primary_oai_doaj_org_article_62d8a490a2a54da5ad6363c7c00d779c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_62d8a490a2a54da5ad6363c7c00d779c
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ISSN
2218-273X
E-ISSN
2218-273X
DOI
10.3390/biom12101511
