A comprehensive characterization of PncA polymorphisms that confer resistance to pyrazinamide
A comprehensive characterization of PncA polymorphisms that confer resistance to pyrazinamide
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Tuberculosis chemotherapy is dependent on the use of the antibiotic pyrazinamide, which is being threatened by emerging drug resistance. Resistance is mediated through mutations in the bacterial gene
pncA
. Methods for testing pyrazinamide susceptibility are difficult and rarely performed, and this means that the full spectrum of
pncA
a...
Alternative Titles
Full title
A comprehensive characterization of PncA polymorphisms that confer resistance to pyrazinamide
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TN_cdi_doaj_primary_oai_doaj_org_article_64b393ee6e854aef8a3dc9823de250ff
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_64b393ee6e854aef8a3dc9823de250ff
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-00721-2
