High-throughput telomere length measurement at nucleotide resolution using the PacBio high fidelity...
High-throughput telomere length measurement at nucleotide resolution using the PacBio high fidelity sequencing platform
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Author / Creator
Tham, Cheng-Yong , Poon, LaiFong , Yan, TingDong , Koh, Javier Yu Peng , Ramlee, Muhammad Khairul , Teoh, Vania Swee Imm , Zhang, Suihan , Cai, Yi , Hong, Zebin , Lee, Gina S. , Liu, Jin , Song, Hai Wei , Hwang, William Ying Khee , Teh, Bin Tean , Tan, Patrick , Xu, Lifeng , Koh, Angela S. , Osato, Motomi and Li, Shang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Telomeres are specialized nucleoprotein structures at the ends of linear chromosomes. The progressive shortening of steady-state telomere length in normal human somatic cells is a promising biomarker for age-associated diseases. However, there remain substantial challenges in quantifying telomere length due to the lack of high-throughput method wit...
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Full title
High-throughput telomere length measurement at nucleotide resolution using the PacBio high fidelity sequencing platform
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TN_cdi_doaj_primary_oai_doaj_org_article_64cb1ffc77e441ea9cb04a62de2be0e9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_64cb1ffc77e441ea9cb04a62de2be0e9
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-35823-7
