Fis1 phosphorylation by Met promotes mitochondrial fission and hepatocellular carcinoma metastasis
Fis1 phosphorylation by Met promotes mitochondrial fission and hepatocellular carcinoma metastasis
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Author / Creator
Yu, Yan , Peng, Xiao-Dan , Qian, Xiao-Jun , Zhang, Kai-Ming , Huang, Xiang , Chen, Yu-Hong , Li, Yun-Tian , Feng, Gong-Kan , Zhang, Hai-Liang , Xu, Xue-Lian , Li, Shun , Li, Xuan , Mai, Jia , Li, Zhi-Ling , Huang, Yun , Yang, Dong , Zhou, Li-Huan , Zhong, Zhuo-Yan , Li, Jun-Dong , Deng, Rong and Zhu, Xiao-Feng
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Met tyrosine kinase, a receptor for a hepatocyte growth factor (HGF), plays a critical role in tumor growth, metastasis, and drug resistance. Mitochondria are highly dynamic and undergo fission and fusion to maintain a functional mitochondrial network. Dysregulated mitochondrial dynamics are responsible for the progression and metastasis of many ca...
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Full title
Fis1 phosphorylation by Met promotes mitochondrial fission and hepatocellular carcinoma metastasis
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TN_cdi_doaj_primary_oai_doaj_org_article_6601f6c66f7649e89ed624b91b63f812
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6601f6c66f7649e89ed624b91b63f812
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ISSN
2059-3635,2095-9907
E-ISSN
2059-3635
DOI
10.1038/s41392-021-00790-2
