Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration
Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Microglia maintain brain homeostasis by removing neuron-derived components such as myelin and cell debris. The evidence linking microglia to neurodegenerative diseases is growing; however, the precise mechanisms remain poorly understood. Herein, we report a neuroprotective role for microglia in the clearance of neuron-released α-synuclein. Neuronal...
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Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration
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TN_cdi_doaj_primary_oai_doaj_org_article_666741e7ee464c8c913aa49d57227aa6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_666741e7ee464c8c913aa49d57227aa6
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15119-w
