The spatial organization of intra-tumour heterogeneity and evolutionary trajectories of metastases i...
The spatial organization of intra-tumour heterogeneity and evolutionary trajectories of metastases in hepatocellular carcinoma
About this item
Full title
Author / Creator
Zhai, Weiwei , Lim, Tony Kiat-Hon , Zhang, Tong , Phang, Su-Ting , Tiang, Zenia , Guan, Peiyong , Ng, Ming-Hwee , Lim, Jia Qi , Yao, Fei , Li, Zheng , Ng, Poh Yong , Yan, Jie , Goh, Brian K. , Chung, Alexander Yaw-Fui , Choo, Su-Pin , Khor, Chiea Chuen , Soon, Wendy Wei-Jia , Sung, Ken Wing-Kin , Foo, Roger Sik-Yin and Chow, Pierce Kah-Hoe
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Hepatocellular carcinoma (HCC) has one of the poorest survival rates among cancers. Using multi-regional sampling of nine resected HCC with different aetiologies, here we construct phylogenetic relationships of these sectors, showing diverse levels of genetic sharing, spanning early to late diversification. Unlike the variegated pattern found in co...
Alternative Titles
Full title
The spatial organization of intra-tumour heterogeneity and evolutionary trajectories of metastases in hepatocellular carcinoma
Authors, Artists and Contributors
Author / Creator
Lim, Tony Kiat-Hon
Zhang, Tong
Phang, Su-Ting
Tiang, Zenia
Guan, Peiyong
Ng, Ming-Hwee
Lim, Jia Qi
Yao, Fei
Li, Zheng
Ng, Poh Yong
Yan, Jie
Goh, Brian K.
Chung, Alexander Yaw-Fui
Choo, Su-Pin
Khor, Chiea Chuen
Soon, Wendy Wei-Jia
Sung, Ken Wing-Kin
Foo, Roger Sik-Yin
Chow, Pierce Kah-Hoe
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_66747f4fa69e494a8136f9ada8520565
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_66747f4fa69e494a8136f9ada8520565
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms14565
