TERRA G-quadruplex RNA interaction with TRF2 GAR domain is required for telomere integrity
TERRA G-quadruplex RNA interaction with TRF2 GAR domain is required for telomere integrity
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Telomere dysfunction causes chromosomal instability which is associated with many cancers and age-related diseases. The non-coding telomeric repeat-containing RNA (TERRA) forms a structural and regulatory component of the telomere that is implicated in telomere maintenance and chromosomal end protection. The basic N-terminal Gly/Arg-rich (GAR) doma...
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Full title
TERRA G-quadruplex RNA interaction with TRF2 GAR domain is required for telomere integrity
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TN_cdi_doaj_primary_oai_doaj_org_article_66afc9aff8e74ec3a03afa244b0f1666
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_66afc9aff8e74ec3a03afa244b0f1666
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-82406-x
