Investigating the In Vivo Effects of Anti-Prion Protein Nanobodies on Prion Disease with AAV Vector
Investigating the In Vivo Effects of Anti-Prion Protein Nanobodies on Prion Disease with AAV Vector
About this item
Full title
Author / Creator
Publisher
Switzerland: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: MDPI AG
Subjects
More information
Scope and Contents
Contents
Prion diseases are fatal neurodegenerative disorders affecting humans and animals, and the central pathogenic event is the conversion of normal prion protein (PrP
) into the pathogenic PrP
isoform. Previous studies have identified nanobodies that specifically recognize PrP
and inhibit the PrP
to PrP
conversion in vitro. In this study...
Alternative Titles
Full title
Investigating the In Vivo Effects of Anti-Prion Protein Nanobodies on Prion Disease with AAV Vector
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_66bc7b01e9e1429993b414c2a2aaa55e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_66bc7b01e9e1429993b414c2a2aaa55e
Other Identifiers
ISSN
2076-0817
E-ISSN
2076-0817
DOI
10.3390/pathogens14020131
