Addition of a carboxy-terminal tail to the normally tailless gonadotropin-releasing hormone receptor...
Addition of a carboxy-terminal tail to the normally tailless gonadotropin-releasing hormone receptor impairs fertility in female mice
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Author / Creator
Toufaily, Chirine , Fortin, Jérôme , Alonso, Carlos Ai , Lapointe, Evelyne , Zhou, Xiang , Santiago-Andres, Yorgui , Lin, Yeu-Farn , Cui, Yiming , Wang, Ying , Devost, Dominic , Roelfsema, Ferdinand , Steyn, Frederik , Hanyaloglu, Aylin C , Hébert, Terence E , Fiordelisio, Tatiana , Boerboom, Derek and Bernard, Daniel J
Publisher
England: eLife Science Publications, Ltd
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English
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Publisher
England: eLife Science Publications, Ltd
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Contents
Gonadotropin-releasing hormone (GnRH) is the primary neuropeptide controlling reproduction in vertebrates. GnRH stimulates follicle-stimulating hormone (FSH) and luteinizing hormone (LH) synthesis via a G-protein-coupled receptor, GnRHR, in the pituitary gland. In mammals, GnRHR lacks a C-terminal cytosolic tail (Ctail) and does not exhibit homolog...
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Full title
Addition of a carboxy-terminal tail to the normally tailless gonadotropin-releasing hormone receptor impairs fertility in female mice
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TN_cdi_doaj_primary_oai_doaj_org_article_67a8eb78b0ce46eab129601c15478f79
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_67a8eb78b0ce46eab129601c15478f79
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.72937
