Distal regulatory elements identified by methylation and hydroxymethylation haplotype blocks from mo...
Distal regulatory elements identified by methylation and hydroxymethylation haplotype blocks from mouse brain
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Author / Creator
Ma, Qin , Xu, Zhengzheng , Lu, Huan , Xu, Ziying , Zhou, Yuanyuan , Yuan, Bifeng and Ci, Weimin
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
5-Hydroxymethylcytosine (5hmC) is an oxidation product of 5-methylcytosine (5mC), and adjacent CpG sites in mammalian genome can be co-methylated and co-hydroxymethylated due to the processivity of DNMT and TET enzymes.
We applied TAB-seq and oxBS-seq to selectively detect 5hmC and 5mC at base resolution in the mouse cortex, olfactory bulb and c...
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Full title
Distal regulatory elements identified by methylation and hydroxymethylation haplotype blocks from mouse brain
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TN_cdi_doaj_primary_oai_doaj_org_article_67bf318ebe8c47d6b51a6ad29443db9e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_67bf318ebe8c47d6b51a6ad29443db9e
Other Identifiers
ISSN
1756-8935
E-ISSN
1756-8935
DOI
10.1186/s13072-018-0248-3