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ArticlesPeer ReviewedFull Text
De novo DNA methylation drives 5hmC accumulation in mouse zygotes
Author / Creator:Amouroux, Rachel ; Nashun, Buhe ; Shirane, Kenjiro ; Nakagawa, Shoma ; Hill, Peter W. S. ; D’Souza, Zelpha ; Nakayama, Manabu ; Matsuda, Masashi ; Turp, Aleksandra ; Ndjetehe, Elodie ; Encheva, Vesela ; Kudo, Nobuaki R. ; Koseki, Haruhiko ; Sasaki, Hiroyuki ; Hajkova, Petra
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2016-02, Vol.18 (2), p.225-233
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PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos
Author / Creator:Nakamura, Toshinobu ; Liu, Yu-Jung ; Nakashima, Hiroyuki ; Umehara, Hiroki ; Inoue, Kimiko ; Matoba, Shogo ; Tachibana, Makoto ; Ogura, Atsuo ; Shinkai, Yoichi ; Nakano, Toru
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-06, Vol.486 (7403), p.415-419
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Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
Author / Creator:Ito, Shinsuke ; D’Alessio, Ana C. ; Taranova, Olena V. ; Hong, Kwonho ; Sowers, Lawrence C. ; Zhang, Yi
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2010-08, Vol.466 (7310), p.1129-1133
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Single-cell 5hmC sequencing reveals chromosome-wide cell-to-cell variability and enables lineage reconstruction
Author / Creator:Mooijman, Dylan ; Dey, Siddharth S ; Boisset, Jean-Charles ; Crosetto, Nicola ; van Oudenaarden, Alexander
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2016-08, Vol.34 (8), p.852-856
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Predicting gene expression state and prioritizing putative enhancers using 5hmC signal
Author / Creator:Gonzalez-Avalos, Edahi ; Onodera, Atsushi ; Samaniego-Castruita, Daniela ; Rao, Anjana ; Ay, Ferhat
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2024-06, Vol.25 (1), p.142-142, Article 142
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Neuron and astrocyte specific 5mC and 5hmC signatures of BDNF’s receptor, TrkB
Author / Creator:Wei, Xiaoran ; Browning, Jack L. ; Olsen, Michelle L.
Publisher:Switzerland: Frontiers Media S.A
Journal title:Frontiers in molecular neuroscience, 2024-08, Vol.17, p.1463437
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Nitric oxide inhibits ten-eleven translocation DNA demethylases to regulate 5mC and 5hmC across the genome
Author / Creator:Palczewski, Marianne B. ; Kuschman, Hannah Petraitis ; Hoffman, Brian M. ; Kathiresan, Venkatesan ; Yang, Hao ; Glynn, Sharon A. ; Wilson, David L. ; Kool, Eric T. ; Montfort, William R. ; Chang, Jenny ; Petenkaya, Aydolun ; Chronis, Constantinos ; Cundari, Thomas R. ; Sappa, Sushma ; Islam, Kabirul ; McVicar, Daniel W. ; Fan, Yu ; Chen, Qingrong ; Meerzaman, Daoud ; Sierk, Michael ; Thomas, Douglas D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-02, Vol.16 (1), p.1732-18, Article 1732
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TET Enzymes and 5hmC Levels in Carcinogenesis and Progression of Breast Cancer: Potential Therapeutic Targets
Author / Creator:Salmerón-Bárcenas, Eric Genaro ; Zacapala-Gómez, Ana Elvira ; Torres-Rojas, Francisco Israel ; Antonio-Véjar, Verónica ; Ávila-López, Pedro Antonio ; Baños-Hernández, Christian Johana ; Núñez-Martínez, Hober Nelson ; Dircio-Maldonado, Roberto ; Martínez-Carrillo, Dinorah Nashely ; Ortiz-Ortiz, Julio ; Jiménez-Wences, Hilda
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-12, Vol.25 (1), p.272
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Global 5mC and 5hmC DNA Levels in Human Sperm Subpopulations with Differentially Protaminated Chromatin in Normo- and Oligoasthenozoospermic Males
Author / Creator:Olszewska, Marta ; Kordyl, Oliwia ; Kamieniczna, Marzena ; Fraczek, Monika ; Jędrzejczak, Piotr ; Kurpisz, Maciej
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2022-04, Vol.23 (9), p.4516
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Tracing cell lineage with 5hmC
Author / Creator:Jarchum, Irene
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2016-09, Vol.13 (9), p.710-711
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Tet1-mediated 5hmC regulates hippocampal neuroinflammation via wnt signaling as a novel mechanism in obstructive sleep apnoea leads to cognitive deficit
Author / Creator:Kong, Yaru ; Ji, Jie ; Zhan, Xiaojun ; Yan, Weiheng ; Liu, Fan ; Ye, Pengfei ; Wang, Shan ; Tai, Jun
Publisher:England: BioMed Central Ltd
Journal title:Journal of neuroinflammation, 2024-08, Vol.21 (1), p.208-21, Article 208
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Social defeat stress induces genome-wide 5mC and 5hmC alterations in the mouse brain
Author / Creator:Kuehner, Janise N ; Walia, Nevin R ; Seong, Rachel ; Li, Yangping ; Martinez-Feduchi, Paula ; Yao, Bing
Publisher:US: Oxford University Press
Journal title:G3 : genes - genomes - genetics, 2023-08, Vol.13 (8)
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β2SP/TET2 complex regulates gene 5hmC modification after cerebral ischemia
Author / Creator:Ma, Xiaohua ; Zhang, Meng ; Yan, Rui ; Wu, Hainan ; Yang, Bo ; Miao, Zhigang
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2021-12, Vol.25 (24), p.11300-11309
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TET2 Promotes Keloid Hyperplasia by Regulating 5hmC Modification in the TGFβ Promoter Region TET2 Promotes Keloid Hyperplasia by Regulating 5hmC Modification in the TGFβ Promoter Region
Author / Creator:Niu C ; Tan S
Publisher:Dove Medical Press
Journal title:Clinical, cosmetic and investigational dermatology, 2023-04, Vol.16, p.1063-1070
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Prenatal Lead (Pb) Exposure and Peripheral Blood DNA Methylation (5mC) and Hydroxymethylation (5hmC) in Mexican Adolescents from the ELEMENT Birth Cohort
Author / Creator:Rygiel, Christine A. ; Goodrich, Jaclyn M. ; Solano-González, Maritsa ; Mercado-García, Adriana ; Hu, Howard ; Téllez-Rojo, Martha M. ; Peterson, Karen E. ; Dolinoy, Dana C.
Publisher:United States: National Institute of Environmental Health Sciences
Journal title:Environmental health perspectives, 2021-06, Vol.129 (6), p.67002
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Sox2 induces glioblastoma cell stemness and tumor propagation by repressing TET2 and deregulating 5hmC and 5mC DNA modifications
Author / Creator:Lopez-Bertoni, Hernando ; Johnson, Amanda ; Rui, Yuan ; Lal, Bachchu ; Sall, Sophie ; Malloy, Maureen ; Coulter, Jonathan B. ; Lugo-Fagundo, Maria ; Shudir, Sweta ; Khela, Harmon ; Caputo, Christopher ; Green, Jordan J. ; Laterra, John
Publisher:London: Nature Publishing Group UK
Journal title:Signal transduction and targeted therapy, 2022-02, Vol.7 (1), p.37-37, Article 37
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Alterations in the Genomic Distribution of 5hmC in In Vivo Aged Human Skin Fibroblasts
Author / Creator:Kołodziej-Wojnar, Paulina ; Borkowska, Joanna ; Wicik, Zofia ; Domaszewska-Szostek, Anna ; Połosak, Jacek ; Cąkała-Jakimowicz, Marta ; Bujanowska, Olga ; Puzianowska-Kuznicka, Monika
Publisher:Switzerland: MDPI
Journal title:International journal of molecular sciences, 2020-12, Vol.22 (1), p.78
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TET2 Promotes Keloid Hyperplasia by Regulating 5hmC Modification in the TGF[beta] Promoter Region
Author / Creator:Niu, Changying ; Tan, Shenxing
Publisher:Dove Medical Press Limited
Journal title:Clinical, cosmetic and investigational dermatology, 2023-04, Vol.16, p.1063
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Fisetin decreases TET1 activity and CCNY/CDK16 promoter 5hmC levels to inhibit the proliferation and invasion of renal cancer stem cell
Author / Creator:Si, Yibing ; Liu, Junfeng ; Shen, Hongliang ; Zhang, Chen ; Wu, Yuanhao ; Huang, Yongyi ; Gong, Zhangbin ; Xue, Jun ; Liu, Te
Publisher:England: John Wiley and Sons Inc
Journal title:Journal of cellular and molecular medicine, 2019-02, Vol.23 (2), p.1095-1105
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Genome-wide 5-hydroxymethylcytosine (5hmC) emerges at early stage of in vitro differentiation of a putative hepatocyte progenitor
Author / Creator:Rodríguez-Aguilera, Jesús Rafael ; Ecsedi, Szilvia ; Goldsmith, Chloe ; Cros, Marie-Pierre ; Domínguez-López, Mariana ; Guerrero-Celis, Nuria ; Pérez-Cabeza de Vaca, Rebeca ; Chemin, Isabelle ; Recillas-Targa, Félix ; Chagoya de Sánchez, Victoria ; Hernández-Vargas, Héctor
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-05, Vol.10 (1), p.7822-7822, Article 7822
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Showing 1 to 20 of 866 results

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De novo DNA methylation drives 5hmC accumulation in mouse zygotes

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PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos

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Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

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Single-cell 5hmC sequencing reveals chromosome-wide cell-to-cell variability and enables lineage reconstruction

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Predicting gene expression state and prioritizing putative enhancers using 5hmC signal

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Neuron and astrocyte specific 5mC and 5hmC signatures of BDNF’s receptor, TrkB

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Nitric oxide inhibits ten-eleven translocation DNA demethylases to regulate 5mC and 5hmC across the genome

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TET Enzymes and 5hmC Levels in Carcinogenesis and Progression of Breast Cancer: Potential Therapeutic Targets

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Global 5mC and 5hmC DNA Levels in Human Sperm Subpopulations with Differentially Protaminated Chromatin in Normo- and Oligoasthenozoospermic Males

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Tracing cell lineage with 5hmC

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Tet1-mediated 5hmC regulates hippocampal neuroinflammation via wnt signaling as a novel mechanism in obstructive sleep apnoea leads to cognitive deficit

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Social defeat stress induces genome-wide 5mC and 5hmC alterations in the mouse brain

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β2SP/TET2 complex regulates gene 5hmC modification after cerebral ischemia

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TET2 Promotes Keloid Hyperplasia by Regulating 5hmC Modification in the TGFβ Promoter Region TET2 Promotes Keloid Hyperplasia by Regulating 5hmC Modification in the TGFβ Promoter Region

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Prenatal Lead (Pb) Exposure and Peripheral Blood DNA Methylation (5mC) and Hydroxymethylation (5hmC) in Mexican Adolescents from the ELEMENT Birth Cohort

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Sox2 induces glioblastoma cell stemness and tumor propagation by repressing TET2 and deregulating 5hmC and 5mC DNA modifications

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Alterations in the Genomic Distribution of 5hmC in In Vivo Aged Human Skin Fibroblasts

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TET2 Promotes Keloid Hyperplasia by Regulating 5hmC Modification in the TGF[beta] Promoter Region

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Fisetin decreases TET1 activity and CCNY/CDK16 promoter 5hmC levels to inhibit the proliferation and invasion of renal cancer stem cell

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Genome-wide 5-hydroxymethylcytosine (5hmC) emerges at early stage of in vitro differentiation of a putative hepatocyte progenitor

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