Growth hormone activates PI3K/Akt signaling and inhibits ROS accumulation and apoptosis in granulosa...
Growth hormone activates PI3K/Akt signaling and inhibits ROS accumulation and apoptosis in granulosa cells of patients with polycystic ovary syndrome
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Author / Creator
Gong, Yan , Luo, Shan , Fan, Ping , Zhu, Huili , Li, Yujing and Huang, Wei
Publisher
London: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
London: BioMed Central Ltd
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Scope and Contents
Contents
Background It is reported that growth hormone (GH) can alleviate oxidative stress (OS) induced apoptosis in some types of cells by activating the PI3K/Akt signaling pathway. This study investigated the role and underlying mechanism of GH in OS and apoptosis in granulosa cells (GCs) of patients with polycystic ovary syndrome (PCOS). Methods Primary...
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Full title
Growth hormone activates PI3K/Akt signaling and inhibits ROS accumulation and apoptosis in granulosa cells of patients with polycystic ovary syndrome
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_68321e5ae7da402a8d0ad9c414601cba
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_68321e5ae7da402a8d0ad9c414601cba
Other Identifiers
ISSN
1477-7827
E-ISSN
1477-7827
DOI
10.1186/s12958-020-00677-x
