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BMAL1 regulates mitochondrial fission and mitophagy through mitochondrial protein BNIP3 and is criti...

BMAL1 regulates mitochondrial fission and mitophagy through mitochondrial protein BNIP3 and is criti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6847cdb6aa6e403082550f8441d6c8df

BMAL1 regulates mitochondrial fission and mitophagy through mitochondrial protein BNIP3 and is critical in the development of dilated cardiomyopathy

About this item

Full title

BMAL1 regulates mitochondrial fission and mitophagy through mitochondrial protein BNIP3 and is critical in the development of dilated cardiomyopathy

Publisher

Beijing: Higher Education Press

Journal title

Protein & cell, 2020-09, Vol.11 (9), p.661-679

Language

English

Formats

Publication information

Publisher

Beijing: Higher Education Press

More information

Scope and Contents

Contents

Dysregulation of circadian rhythms associates with cardiovascular disorders. It is known that deletion of the core circadian gene Bmal1 in mice causes dilated cardiomyopathy. However, the biological rhythm regulation system in mouse is very different from that of humans. Whether BMAL1 plays a role in regulating human heart function remains unclear....

Alternative Titles

Full title

BMAL1 regulates mitochondrial fission and mitophagy through mitochondrial protein BNIP3 and is critical in the development of dilated cardiomyopathy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6847cdb6aa6e403082550f8441d6c8df

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6847cdb6aa6e403082550f8441d6c8df

Other Identifiers

ISSN

1674-800X

E-ISSN

1674-8018

DOI

10.1007/s13238-020-00713-x

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