Engineered bacterial outer membrane vesicles encapsulating oncolytic adenoviruses enhance the effica...
Engineered bacterial outer membrane vesicles encapsulating oncolytic adenoviruses enhance the efficacy of cancer virotherapy by augmenting tumor cell autophagy
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Author / Creator
Ban, Weiyue , Sun, Mengchi , Huang, Hanwei , Huang, Wanxu , Pan, Siwei , Liu, Pengfei , Li, Bingwu , Cheng, Zhenguo , He, Zhonggui , Liu, Funan and Sun, Jin
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
Oncolytic adenovirus (Ad) infection promotes intracellular autophagy in tumors. This could kill cancer cells and contribute to Ads-mediated anticancer immunity. However, the low intratumoral content of intravenously delivered Ads could be insufficient to efficiently activate tumor over-autophagy. Herein, we report bacterial outer membrane vesicles...
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Full title
Engineered bacterial outer membrane vesicles encapsulating oncolytic adenoviruses enhance the efficacy of cancer virotherapy by augmenting tumor cell autophagy
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_6919a0edf7874583ba33724a87614d24
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6919a0edf7874583ba33724a87614d24
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-38679-z
