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PTN from Leydig cells activates SDC2 and modulates human spermatogonial stem cell proliferation and...

PTN from Leydig cells activates SDC2 and modulates human spermatogonial stem cell proliferation and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_69982d39e5114fd99134fd2de41cc23d

PTN from Leydig cells activates SDC2 and modulates human spermatogonial stem cell proliferation and survival via GFRA1

About this item

Full title

PTN from Leydig cells activates SDC2 and modulates human spermatogonial stem cell proliferation and survival via GFRA1

Publisher

England: BioMed Central Ltd

Journal title

Biological research, 2024-09, Vol.57 (1), p.66-15, Article 66

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Spermatogonial stem cells (SSCs) are essential for the maintenance and initiation of male spermatogenesis. Despite the advances in understanding SSC biology in mouse models, the mechanisms underlying human SSC development remain elusive.
Here, we analyzed the signaling pathways involved in SSC regulation by testicular somatic cells using single-...

Alternative Titles

Full title

PTN from Leydig cells activates SDC2 and modulates human spermatogonial stem cell proliferation and survival via GFRA1

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_69982d39e5114fd99134fd2de41cc23d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_69982d39e5114fd99134fd2de41cc23d

Other Identifiers

ISSN

0717-6287,0716-9760

E-ISSN

0717-6287

DOI

10.1186/s40659-024-00546-6

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