PTN from Leydig cells activates SDC2 and modulates human spermatogonial stem cell proliferation and...
PTN from Leydig cells activates SDC2 and modulates human spermatogonial stem cell proliferation and survival via GFRA1
About this item
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Author / Creator
Zhao, Xueheng , Liu, Lvjun , Huang, Zenghui , Zhu, Fang , Zhang, Huan and Zhou, Dai
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Spermatogonial stem cells (SSCs) are essential for the maintenance and initiation of male spermatogenesis. Despite the advances in understanding SSC biology in mouse models, the mechanisms underlying human SSC development remain elusive.
Here, we analyzed the signaling pathways involved in SSC regulation by testicular somatic cells using single-...
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Full title
PTN from Leydig cells activates SDC2 and modulates human spermatogonial stem cell proliferation and survival via GFRA1
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_69982d39e5114fd99134fd2de41cc23d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_69982d39e5114fd99134fd2de41cc23d
Other Identifiers
ISSN
0717-6287,0716-9760
E-ISSN
0717-6287
DOI
10.1186/s40659-024-00546-6