Serial interactome capture of the human cell nucleus
Serial interactome capture of the human cell nucleus
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Novel RNA-guided cellular functions are paralleled by an increasing number of RNA-binding proteins (RBPs). Here we present ‘serial RNA interactome capture’ (serIC), a multiple purification procedure of ultraviolet-crosslinked poly(A)–RNA–protein complexes that enables global RBP detection with high specificity. We apply serIC to the nuclei of proli...
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Full title
Serial interactome capture of the human cell nucleus
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TN_cdi_doaj_primary_oai_doaj_org_article_69e220f40da44ba3bec616fc504d19de
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_69e220f40da44ba3bec616fc504d19de
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms11212
