Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mes...
Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Fibroblastic tumour stroma comprising mesenchymal stem cells (MSCs) and cancer-associated fibroblasts (CAFs) promotes the invasive and metastatic properties of tumour cells. Here we show that activated CD8
+
T cell-derived extracellular vesicles (EVs) interrupt fibroblastic stroma-mediated tumour progression. Activated CD8
+
T cells fro...
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Full title
Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells
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TN_cdi_doaj_primary_oai_doaj_org_article_6a2cc30b31e1417ba6551dd38e924e4a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6a2cc30b31e1417ba6551dd38e924e4a
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-02865-1