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Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mes...

Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mes...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6a2cc30b31e1417ba6551dd38e924e4a

Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells

About this item

Full title

Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-01, Vol.9 (1), p.435-11, Article 435

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Fibroblastic tumour stroma comprising mesenchymal stem cells (MSCs) and cancer-associated fibroblasts (CAFs) promotes the invasive and metastatic properties of tumour cells. Here we show that activated CD8
+
T cell-derived extracellular vesicles (EVs) interrupt fibroblastic stroma-mediated tumour progression. Activated CD8
+
T cells fro...

Alternative Titles

Full title

Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6a2cc30b31e1417ba6551dd38e924e4a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6a2cc30b31e1417ba6551dd38e924e4a

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-02865-1

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