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Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism

Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6a8adde43f8e4a568fb7abbf52f498c8

Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism

About this item

Full title

Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-06, Vol.11 (1), p.2695-16, Article 2695

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Obesity and type 2 diabetes (T2D) are metabolic disorders influenced by lifestyle and genetic factors that are characterized by insulin resistance in skeletal muscle, a prominent site of glucose disposal. Numerous genetic variants have been associated with obesity and T2D, of which the majority are located in non-coding DNA regions. This suggests t...

Alternative Titles

Full title

Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6a8adde43f8e4a568fb7abbf52f498c8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6a8adde43f8e4a568fb7abbf52f498c8

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-16537-6

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