Low oral dose of 4-methylumbelliferone reduces glial scar but is insufficient to induce functional r...
Low oral dose of 4-methylumbelliferone reduces glial scar but is insufficient to induce functional recovery after spinal cord injury
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Spinal cord injury (SCI) induces the upregulation of chondroitin sulfate proteoglycans (CSPGs) at the glial scar and inhibits neuroregeneration. Under normal physiological condition, CSPGs interact with hyaluronan (HA) and other extracellular matrix on the neuronal surface forming a macromolecular structure called perineuronal nets (PNNs) which reg...
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Low oral dose of 4-methylumbelliferone reduces glial scar but is insufficient to induce functional recovery after spinal cord injury
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TN_cdi_doaj_primary_oai_doaj_org_article_6a94ae27635c48be96447c35b9adf4cf
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6a94ae27635c48be96447c35b9adf4cf
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-46539-5
