Clinical association analysis of ependymomas and pilocytic astrocytomas reveals elevated FGFR3 and F...
Clinical association analysis of ependymomas and pilocytic astrocytomas reveals elevated FGFR3 and FGFR1 expression in aggressive ependymomas
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England: BioMed Central
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Language
English
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England: BioMed Central
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Fibroblast growth factor receptors (FGFRs) are well-known proto-oncogenes in several human malignancies and are currently therapeutically targeted in clinical trials. Among glioma subtypes, activating FGFR1 alterations have been observed in a subpopulation of pilocytic astrocytomas while FGFR3 fusions occur in IDH wild-type diffuse gliomas, resulti...
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Clinical association analysis of ependymomas and pilocytic astrocytomas reveals elevated FGFR3 and FGFR1 expression in aggressive ependymomas
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TN_cdi_doaj_primary_oai_doaj_org_article_6b146cdd7b804c81a39d40ca1851b35f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6b146cdd7b804c81a39d40ca1851b35f
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-017-3274-9
