Whole genome sequencing of 378 prostate cancer metastases reveals tissue selectivity for mismatch de...
Whole genome sequencing of 378 prostate cancer metastases reveals tissue selectivity for mismatch deficiency with potential therapeutic implications
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Survival of patients with metastatic castration-resistant prostate cancer (mCRPC) depends on the site of metastatic dissemination.
Patients with mCRPC were prospectively included in the CPCT-02 metastatic site biopsy study. We evaluated whole genome sequencing (WGS) of 378 mCRPC metastases to understand the genetic traits that affect metastatic...
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Full title
Whole genome sequencing of 378 prostate cancer metastases reveals tissue selectivity for mismatch deficiency with potential therapeutic implications
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TN_cdi_doaj_primary_oai_doaj_org_article_6b18447be81443fd93daba00feafc681
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6b18447be81443fd93daba00feafc681
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ISSN
1756-994X
E-ISSN
1756-994X
DOI
10.1186/s13073-025-01445-5
