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Quiescence enables unrestricted cell fate in naive embryonic stem cells

Quiescence enables unrestricted cell fate in naive embryonic stem cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6b1a1bc377ca40f2bfe4471b19c2237e

Quiescence enables unrestricted cell fate in naive embryonic stem cells

About this item

Full title

Quiescence enables unrestricted cell fate in naive embryonic stem cells

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-02, Vol.15 (1), p.1721-19, Article 1721

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Quiescence in stem cells is traditionally considered as a state of inactive dormancy or with poised potential. Naive mouse embryonic stem cells (ESCs) can enter quiescence spontaneously or upon inhibition of MYC or fatty acid oxidation, mimicking embryonic diapause in vivo. The molecular underpinning and developmental potential of quiescent ESCs (q...

Alternative Titles

Full title

Quiescence enables unrestricted cell fate in naive embryonic stem cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6b1a1bc377ca40f2bfe4471b19c2237e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6b1a1bc377ca40f2bfe4471b19c2237e

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-46121-1

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