Inhibiting MARSs reduces hyperhomocysteinemia‐associated neural tube and congenital heart defects
Inhibiting MARSs reduces hyperhomocysteinemia‐associated neural tube and congenital heart defects
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Author / Creator
Mei, Xinyu , Qi, Dashi , Zhang, Ting , Zhao, Ying , Jin, Li , Hou, Junli , Wang, Jianhua , Lin, Yan , Xue, Yu , Zhu, Pingping , Liu, Zexian , Huang, Lei , Nie, Ji , Si, Wen , Ma, Jingyi , Ye, Jianhong , Finnell, Richard H , Saiyin, Hexige , Wang, Hongyan , Zhao, Jianyuan , Zhao, Shimin and Xu, Wei
Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Hyperhomocysteinemia is a common metabolic disorder that imposes major adverse health consequences. Reducing homocysteine levels, however, is not always effective against hyperhomocysteinemia‐associated pathologies. Herein, we report the potential roles of methionyl‐tRNA synthetase (MARS)‐generated homocysteine signals in neural tube defects (NTDs)...
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Full title
Inhibiting MARSs reduces hyperhomocysteinemia‐associated neural tube and congenital heart defects
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TN_cdi_doaj_primary_oai_doaj_org_article_6b50f0570cb5436ab3a125835132de2d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6b50f0570cb5436ab3a125835132de2d
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ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.201809469
