Targeting brain lesions of non-small cell lung cancer by enhancing CCL2-mediated CAR-T cell migratio...
Targeting brain lesions of non-small cell lung cancer by enhancing CCL2-mediated CAR-T cell migration
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Metastatic non-small cell lung cancer (NSCLC) remains largely incurable and the prognosis is extremely poor once it spreads to the brain. In particular, in patients with brain metastases, the blood brain barrier (BBB) remains a significant obstacle for the biodistribution of antitumor drugs and immune cells. Here we report that chimeric antigen rec...
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Full title
Targeting brain lesions of non-small cell lung cancer by enhancing CCL2-mediated CAR-T cell migration
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TN_cdi_doaj_primary_oai_doaj_org_article_6b5527f7df4141638fa2ab38499267ce
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6b5527f7df4141638fa2ab38499267ce
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-29647-0
