Internalized GPCRs as Potential Therapeutic Targets for the Management of Pain
Internalized GPCRs as Potential Therapeutic Targets for the Management of Pain
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Lausanne: Frontiers Research Foundation
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Language
English
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Lausanne: Frontiers Research Foundation
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Contents
Peripheral and central neurons in the pain pathway are well equipped to detect and respond to extracellular stimuli such as pro-inflammatory mediators and neurotransmitters through the cell surface expression of receptors that can mediate rapid intracellular signaling. Following injury or infection, activation of cell surface G protein-coupled rece...
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Internalized GPCRs as Potential Therapeutic Targets for the Management of Pain
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TN_cdi_doaj_primary_oai_doaj_org_article_6c4549998de54b78bfc2d6ea2bed3f2a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6c4549998de54b78bfc2d6ea2bed3f2a
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ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2019.00273