A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0
A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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We present a new approach for macromolecular structure determination from multiple particles in electron cryo-tomography (cryo-ET) data sets. Whereas existing subtomogram averaging approaches are based on 3D data models, we propose to optimise a regularised likelihood target that approximates a function of the 2D experimental images. In addition, a...
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A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0
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TN_cdi_doaj_primary_oai_doaj_org_article_6c4718742c584f12937545f4d66af20f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6c4718742c584f12937545f4d66af20f
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.83724
