cAMP-dependent regulation of HCN4 controls the tonic entrainment process in sinoatrial node pacemake...
cAMP-dependent regulation of HCN4 controls the tonic entrainment process in sinoatrial node pacemaker cells
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Author / Creator
Fenske, Stefanie , Hennis, Konstantin , Rötzer, René D. , Brox, Verena F. , Becirovic, Elvir , Scharr, Andreas , Gruner, Christian , Ziegler, Tilman , Mehlfeld, Verena , Brennan, Jaclyn , Efimov, Igor R. , Pauža, Audrys G. , Moser, Markus , Wotjak, Carsten T. , Kupatt, Christian , Gönner, Rasmus , Zhang, Rai , Zhang, Henggui , Zong, Xiangang , Biel, Martin and Wahl-Schott, Christian
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
It is highly debated how cyclic adenosine monophosphate-dependent regulation (CDR) of the major pacemaker channel HCN4 in the sinoatrial node (SAN) is involved in heart rate regulation by the autonomic nervous system. We addressed this question using a knockin mouse line expressing cyclic adenosine monophosphate-insensitive HCN4 channels. This mous...
Alternative Titles
Full title
cAMP-dependent regulation of HCN4 controls the tonic entrainment process in sinoatrial node pacemaker cells
Authors, Artists and Contributors
Author / Creator
Hennis, Konstantin
Rötzer, René D.
Brox, Verena F.
Becirovic, Elvir
Scharr, Andreas
Gruner, Christian
Ziegler, Tilman
Mehlfeld, Verena
Brennan, Jaclyn
Efimov, Igor R.
Pauža, Audrys G.
Moser, Markus
Wotjak, Carsten T.
Kupatt, Christian
Gönner, Rasmus
Zhang, Rai
Zhang, Henggui
Zong, Xiangang
Biel, Martin
Wahl-Schott, Christian
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_6c6af2794e4b4707a82af208feb04493
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6c6af2794e4b4707a82af208feb04493
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-19304-9
