Clinicopathological and mutational analyses of colorectal cancer with mutations in the POLE gene
Clinicopathological and mutational analyses of colorectal cancer with mutations in the POLE gene
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United States: John Wiley & Sons, Inc
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Language
English
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Publisher
United States: John Wiley & Sons, Inc
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Here, we investigated the clinicopathological and mutation profiles of colorectal cancer (CRC) with POLE mutations. Whole‐exome sequencing was performed in 910 surgically resected primary CRCs. Tumors exceeding 500 counts of nonsynonymous single nucleotide variants (SNVs) were classified as hypermutators, whereas the remaining were classified as no...
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Full title
Clinicopathological and mutational analyses of colorectal cancer with mutations in the POLE gene
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TN_cdi_doaj_primary_oai_doaj_org_article_6cef931b1bb64ffc9ba309f7768a0dfd
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6cef931b1bb64ffc9ba309f7768a0dfd
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ISSN
2045-7634
E-ISSN
2045-7634
DOI
10.1002/cam4.2344
