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Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross‐toler...

Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross‐toler...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6e1d009f1927482eb93bc81bb4cc11c2

Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross‐tolerance

About this item

Full title

Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross‐tolerance

Publisher

London: Nature Publishing Group UK

Journal title

EMBO molecular medicine, 2014-09, Vol.6 (9), p.1191-1204

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Skin dendritic cells (DCs) control the immunogenicity of cutaneously administered vaccines. Antigens targeted to DCs via the C‐type lectin Langerin/CD207 are cross‐presented to CD8
+
T cells
in vivo
. We investigated the relative roles of Langerhans cells (LCs) and Langerin
+
dermal DCs (dDCs) in different vaccination settings. Po...

Alternative Titles

Full title

Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross‐tolerance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6e1d009f1927482eb93bc81bb4cc11c2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6e1d009f1927482eb93bc81bb4cc11c2

Other Identifiers

ISSN

1757-4676

E-ISSN

1757-4684

DOI

10.15252/emmm.201303283

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