Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross‐toler...
Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross‐tolerance
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Skin dendritic cells (DCs) control the immunogenicity of cutaneously administered vaccines. Antigens targeted to DCs via the C‐type lectin Langerin/CD207 are cross‐presented to CD8
+
T cells
in vivo
. We investigated the relative roles of Langerhans cells (LCs) and Langerin
+
dermal DCs (dDCs) in different vaccination settings. Po...
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Full title
Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross‐tolerance
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TN_cdi_doaj_primary_oai_doaj_org_article_6e1d009f1927482eb93bc81bb4cc11c2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6e1d009f1927482eb93bc81bb4cc11c2
Other Identifiers
ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.201303283