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Viability of HepG2 and MCF-7 cells is not correlated with mitochondrial bioenergetics

Viability of HepG2 and MCF-7 cells is not correlated with mitochondrial bioenergetics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6eaf808dbbbf4c99a010823d320edd36

Viability of HepG2 and MCF-7 cells is not correlated with mitochondrial bioenergetics

About this item

Full title

Viability of HepG2 and MCF-7 cells is not correlated with mitochondrial bioenergetics

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2023-07, Vol.13 (1), p.10822-10822, Article 10822

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Alterations in metabolism are a hallmark of cancer. It is unclear if oxidative phosphorylation (OXPHOS) is necessary for tumour cell survival. In this study, we investigated the effects of severe hypoxia, site-specific inhibition of respiratory chain (RC) components, and uncouplers on necrotic and apoptotic markers in 2D-cultured HepG2 and MCF-7 tu...

Alternative Titles

Full title

Viability of HepG2 and MCF-7 cells is not correlated with mitochondrial bioenergetics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6eaf808dbbbf4c99a010823d320edd36

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6eaf808dbbbf4c99a010823d320edd36

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-023-37677-x

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