P62 accumulates through neuroanatomical circuits in response to tauopathy propagation
P62 accumulates through neuroanatomical circuits in response to tauopathy propagation
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Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Contents
In Alzheimer's disease and related tauopathies, trans-synaptic transfer and accumulation of pathological tau from donor to recipient neurons is thought to contribute to disease progression, but the underlying mechanisms are poorly understood. Using complementary in vivo and in vitro models, we examined the relationship between these two processes a...
Alternative Titles
Full title
P62 accumulates through neuroanatomical circuits in response to tauopathy propagation
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TN_cdi_doaj_primary_oai_doaj_org_article_6ec10d2a588a40fb82206e796520623e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6ec10d2a588a40fb82206e796520623e
Other Identifiers
ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-021-01280-w
