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Integrative solution structure of PTBP1-IRES complex reveals strong compaction and ordering with res...

Integrative solution structure of PTBP1-IRES complex reveals strong compaction and ordering with res...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6ecfd082137440199e61e0254d4f1997

Integrative solution structure of PTBP1-IRES complex reveals strong compaction and ordering with residual conformational flexibility

About this item

Full title

Integrative solution structure of PTBP1-IRES complex reveals strong compaction and ordering with residual conformational flexibility

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2023-10, Vol.14 (1), p.6429-6429, Article 6429

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

RNA-binding proteins (RBPs) are crucial regulators of gene expression, often composed of defined domains interspersed with flexible, intrinsically disordered regions. Determining the structure of ribonucleoprotein (RNP) complexes involving such RBPs necessitates integrative structural modeling due to their lack of a single stable state. In this stu...

Alternative Titles

Full title

Integrative solution structure of PTBP1-IRES complex reveals strong compaction and ordering with residual conformational flexibility

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6ecfd082137440199e61e0254d4f1997

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6ecfd082137440199e61e0254d4f1997

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-023-42012-z

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