Integrated genomics and comprehensive validation reveal drivers of genomic evolution in esophageal a...
Integrated genomics and comprehensive validation reveal drivers of genomic evolution in esophageal adenocarcinoma
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Esophageal adenocarcinoma (EAC) is associated with a marked genomic instability, which underlies disease progression and development of resistance to treatment. In this study, we used an integrated genomics approach to identify a genomic instability signature. Here we show that elevated expression of this signature correlates with poor survival in...
Alternative Titles
Full title
Integrated genomics and comprehensive validation reveal drivers of genomic evolution in esophageal adenocarcinoma
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TN_cdi_doaj_primary_oai_doaj_org_article_6f113318075d4e0bb3590bebd59eb8e1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6f113318075d4e0bb3590bebd59eb8e1
Other Identifiers
ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-021-02125-x
