Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer's Disease
Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer's Disease
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Switzerland: Frontiers Research Foundation
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Language
English
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Switzerland: Frontiers Research Foundation
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Contents
Alzheimer's disease (AD) is the most common neurodegenerative disorder, which is clinically associated with a global cognitive decline and progressive loss of memory and reasoning. According to the prevailing amyloid cascade hypothesis of AD, increased soluble amyloid-β (Aβ) oligomer levels impair the synaptic functions and augment calcium dyshomeo...
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Full title
Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer's Disease
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TN_cdi_doaj_primary_oai_doaj_org_article_6f679eb2278c49e0b4c93bf596c990eb
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6f679eb2278c49e0b4c93bf596c990eb
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ISSN
1662-4548,1662-453X
E-ISSN
1662-453X
DOI
10.3389/fnins.2018.00963
