Bone marrow mesenchymal stem cell-derived exosomes protect cartilage damage and relieve knee osteoar...
Bone marrow mesenchymal stem cell-derived exosomes protect cartilage damage and relieve knee osteoarthritis pain in a rat model of osteoarthritis
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Author / Creator
He, Lei , He, Tianwei , Xing, Jianghao , Zhou, Qing , Fan, Lei , Liu, Can , Chen, Yuyong , Wu, Depeng , Tian, Zhenming , Liu, Bin and Rong, Limin
Publisher
London: BioMed Central Ltd
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Language
English
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Publisher
London: BioMed Central Ltd
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Background This study aimed to investigate the effect of bone marrow mesenchymal stem cell (BMSC)-derived exosome injection on cartilage damage and pain relief in both in vitro and in vivo models of osteoarthritis (OA). Methods The BMSCs were extracted from rat bone marrow of the femur and tibia. Chondrocytes were treated with IL-1[beta] to establi...
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Bone marrow mesenchymal stem cell-derived exosomes protect cartilage damage and relieve knee osteoarthritis pain in a rat model of osteoarthritis
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TN_cdi_doaj_primary_oai_doaj_org_article_7022fe5df37542648eb9b02a2f11ea32
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7022fe5df37542648eb9b02a2f11ea32
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ISSN
1757-6512
E-ISSN
1757-6512
DOI
10.1186/s13287-020-01781-w